Mildly Elevated Liver Transaminase Levels in the Asymptomatic Patient

AFP March 15, 2005, Vol. 71, No. 6; Green RM, Flamm S.  AGA technical review on the evaluation of liver chemistry tests.  Gastroenterology 2002; 123: 1367-84.

Note: ALT is thought to be more specific than AST for hepatic injury because it is present mainly in the cytosol of the liver and in low concentrations elsewhere.


H & P:


Lifestyle Modification

Follow up and Imaging

If U/S is negative

Liver biopsy?


Etiology when less than 5X normal
Common hepatic causes:

Less common hepatic causes

Nonhepatic causes